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There is also a literature
2024-04-10
There is also a literature on the impact of commodity (consumption) taxation under imperfect competition. Besley (1989) applies a Cournot model, in which production takes place under IRS and in which free entry leads to an excessive number of firms in the market. Introducing a distortive specific co
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The central problem in amnesia developing following impairme
2024-04-10
The central problem in amnesia developing following impairment of long-term memory consolidation or reconsolidation is a question of the underlying mechanisms, whether it is caused by impairment of retrieval or memory storage mechanisms [3,8,9,[15], [16], [17], [18]]. To answer this question, severa
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The role of DHT in early
2024-04-10
The role of DHT in early teleost embryogenesis is not entirely clear or established, however additional studies that treat fish embryos to DHT or to specific srd5a inhibitors at critical stages of development (i.e. prior to sex differentiation) will shed light on the early functions of this androgen
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The synthesis of compounds in which the ethyl linker
2024-04-10
The synthesis of compounds in which the ethyl linker has been modified to the carbamate and urea derivatives , and is shown in . Thus the diamine was reacted with glycolic Tirapazamine to give the alcohol followed by Mitsunobu reaction with phthalimide to give . Deprotection with hydrazine gave
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Hypoxia induced replication arrest has been
2024-04-10
Hypoxia-induced replication arrest has been demonstrated in a variety of organisms in addition to mammals; including Zebrafish , , and (brine shrimp) which have been shown to survive for 4 years and longer in anoxic conditions . Despite this breadth of study, little is known about the mechanism of h
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br Materials and methods br Results
2024-04-10
Materials and methods Results Discussion In the present study, we found that SSTR2, SSTR5, and DA2R proteins are expressed in ACTH-positive dopamine hydrochloride in healthy canine pituitary glands, with particularly high positive cell ratios in the intermediate lobes. Somatostatin has bee
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Estrogen exerts its genomic action via estrogen nuclear rece
2024-04-10
Estrogen exerts its genomic action via PHA-680632 nuclear receptor: ERα and ERβ. The distribution of ERα and/or ERβ positive neurons in CNS of different species has been mapped extensively by various methods [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], although there are some differe
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Mifepristone Previous investigations have established that a
2024-04-10
Previous investigations have established that aromatase activity is regulated via two different pathways in a tissue-specific manner. The first is a slower transcription regulatory pathway that involves an alteration in gene transcription and represents what is classically thought of as the way by w
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The current findings proved that citral treatment induced mi
2024-04-10
The current findings proved that citral treatment induced mitochondrial-mediated apoptotic cell death in both HCT116 and HT29 through the p53 and ROS. As such, citral promoted apoptosis as evident by the externalization of PS and dissipation of Δψm at 24h of treatment in HCT116 and HT29 cells. These
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Patients with cardiovascular disorders typically have lower
2024-04-10
Patients with cardiovascular disorders typically have lower plasma apelin levels than matched healthy controls. For example, plasma apelin levels are reduced in patients with coronary artery disease (CAD), and among CAD patients with unstable angina or acute myocardial infraction there is a further
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In summary the CV and renal benefits of sacubitril valsartan
2024-04-10
In summary, the CV and renal benefits of sacubitril/valsartan in HF patients are attributed to the increased levels of peptides that are degraded by neprilysin and the simultaneous inhibition of the effects of AT1 receptor by valsartan (Fig. 1). Physical and chemical properties Sacubitril/Valsa
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Histochemical analyses using antibody or cDNA probes reveal
2024-04-09
Histochemical analyses using antibody or cDNA probes reveal the precise cellular location of the 12S-lipoxygenases in tissues of interest. An immunohistochemical study in various rat tissues showed specific expression of the leukocyte-type 12S-lipoxygenase in macrophages in lung and spleen [27]. In
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br Conflict of interest br Introduction The Piezo proteins P
2024-04-09
Conflict of interest Introduction The Piezo proteins, Piezo1/FAM38A and Piezo2/FAM38B, are multi-pass transmembrane proteins that have been identified as mechanically-activated (MA) homomultimeric, pore-forming ion channels [1,2]. Piezo1 is broadly expressed with its highest expression in blad
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Corticosterone induced inhibition of OCT mediated
2024-04-09
Corticosterone-induced inhibition of OCT-mediated transport is rapid and appears to involve direct interaction of the steroid with the transporter at a specific site. Volk et al. (2003) studied OCT2-mediated transport by measuring substrate-induced currents using patch clamp of Xenopus oocytes exog
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In the current study adiponectin receptors expressions were
2024-04-09
In the current study, adiponectin receptors expressions were detected in both cell lines. AdipoR2 showed equal expression levels, whereas AdipoR1 possessed different expression levels in both cell lines. There was a significant increase in the AdipoR1 mRNA levels in cell lines according to AdipoR2 m
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